Combined analysis of dissimilar promoter accessibility and gene expression profiles identifies tissue-specific genes and actively repressed networks

Combined analysis of dissimilar promoter accessibility and gene expression profiles identifies tissue-specific genes and actively repressed networks

Abstract Background The assay for transposase-accessible chromatin (ATAC-seq) is a powerful method to examine chromatin accessibility. While many studies have reported a positive correlation between gene expression and promoter accessibility, few have investigated the genes that deviate from this tr...

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Bibliographic Details
Main Authors: Rebekah R. Starks, Anilisa Biswas, Ashish Jain, Geetu Tuteja
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Epigenetics & Chromatin
Subjects:
ATAC-seq
Gene regulation
RNA-seq
Promoter coverage
Tissue-specific genes
Gene networks
Online Access:http://link.springer.com/article/10.1186/s13072-019-0260-2

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http://link.springer.com/article/10.1186/s13072-019-0260-2

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