Improvement in regional CBF by L-serine contributes to its neuroprotective effect in rats after focal cerebral ischemia.

To investigate the mechanisms underlying the neuroprotective effect of L-serine, permanent focal cerebral ischemia was induced by occlusion of the middle cerebral artery while monitoring cerebral blood flow (CBF). Rats were divided into control and L-serine-treated groups after middle cerebral arter...

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Bibliographic Details
Main Authors: Tao-Jie Ren, Ren Qiang, Zheng-Lin Jiang, Guo-Hua Wang, Li Sun, Rui Jiang, Guang-Wei Zhao, Le-Yang Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3692549?pdf=render