PD-L1 Expression on Circulating Tumour Cells May Be Predictive of Response to Regorafenib in Patients Diagnosed with Chemorefractory Metastatic Colorectal Cancer

PD-L1 Expression on Circulating Tumour Cells May Be Predictive of Response to Regorafenib in Patients Diagnosed with Chemorefractory Metastatic Colorectal Cancer

<b>Keywords: </b>chemorefractory metastatic colorectal cancer; regorafenib; circulating tumour cells; PD-L1; PLR; liquid biopsy; acquired resistance; targeted therapy

Bibliographic Details
Main Authors: Lucrezia Raimondi, Filippo Maria Raimondi, Laura Di Benedetto, Giuseppe Cimino, Gian Paolo Spinelli
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
n/a
Online Access:https://www.mdpi.com/1422-0067/21/18/6907
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spelling doaj-164baf6e45294635b1f27d18e8ffebbb2020-11-25T03:32:35ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-09-01216907690710.3390/ijms21186907PD-L1 Expression on Circulating Tumour Cells May Be Predictive of Response to Regorafenib in Patients Diagnosed with Chemorefractory Metastatic Colorectal CancerLucrezia Raimondi0Filippo Maria Raimondi1Laura Di Benedetto2Giuseppe Cimino3Gian Paolo Spinelli4UOC Territorial Oncology of Aprilia, AUSL Latina, University of Rome Sapienza, 04011 Aprilia, ItalyBiostatistical Consultant, 00197 Rome, ItalyBIOS SpA, 00197 Rome, ItalyUOC Territorial Oncology of Aprilia, AUSL Latina, University of Rome Sapienza, 04011 Aprilia, ItalyUOC Territorial Oncology of Aprilia, AUSL Latina, University of Rome Sapienza, 04011 Aprilia, Italy<b>Keywords: </b>chemorefractory metastatic colorectal cancer; regorafenib; circulating tumour cells; PD-L1; PLR; liquid biopsy; acquired resistance; targeted therapyhttps://www.mdpi.com/1422-0067/21/18/6907n/a
collection DOAJ
language English
format Article
sources DOAJ
author Lucrezia Raimondi
Filippo Maria Raimondi
Laura Di Benedetto
Giuseppe Cimino
Gian Paolo Spinelli
spellingShingle Lucrezia Raimondi
Filippo Maria Raimondi
Laura Di Benedetto
Giuseppe Cimino
Gian Paolo Spinelli
PD-L1 Expression on Circulating Tumour Cells May Be Predictive of Response to Regorafenib in Patients Diagnosed with Chemorefractory Metastatic Colorectal Cancer
International Journal of Molecular Sciences
n/a
author_facet Lucrezia Raimondi
Filippo Maria Raimondi
Laura Di Benedetto
Giuseppe Cimino
Gian Paolo Spinelli
author_sort Lucrezia Raimondi
title PD-L1 Expression on Circulating Tumour Cells May Be Predictive of Response to Regorafenib in Patients Diagnosed with Chemorefractory Metastatic Colorectal Cancer
title_short PD-L1 Expression on Circulating Tumour Cells May Be Predictive of Response to Regorafenib in Patients Diagnosed with Chemorefractory Metastatic Colorectal Cancer
title_full PD-L1 Expression on Circulating Tumour Cells May Be Predictive of Response to Regorafenib in Patients Diagnosed with Chemorefractory Metastatic Colorectal Cancer
title_fullStr PD-L1 Expression on Circulating Tumour Cells May Be Predictive of Response to Regorafenib in Patients Diagnosed with Chemorefractory Metastatic Colorectal Cancer
title_full_unstemmed PD-L1 Expression on Circulating Tumour Cells May Be Predictive of Response to Regorafenib in Patients Diagnosed with Chemorefractory Metastatic Colorectal Cancer
title_sort pd-l1 expression on circulating tumour cells may be predictive of response to regorafenib in patients diagnosed with chemorefractory metastatic colorectal cancer
publisher MDPI AG
series International Journal of Molecular Sciences
issn 1661-6596
1422-0067
publishDate 2020-09-01
description <b>Keywords: </b>chemorefractory metastatic colorectal cancer; regorafenib; circulating tumour cells; PD-L1; PLR; liquid biopsy; acquired resistance; targeted therapy
topic n/a
url https://www.mdpi.com/1422-0067/21/18/6907
work_keys_str_mv AT lucreziaraimondi pdl1expressiononcirculatingtumourcellsmaybepredictiveofresponsetoregorafenibinpatientsdiagnosedwithchemorefractorymetastaticcolorectalcancer
AT filippomariaraimondi pdl1expressiononcirculatingtumourcellsmaybepredictiveofresponsetoregorafenibinpatientsdiagnosedwithchemorefractorymetastaticcolorectalcancer
AT lauradibenedetto pdl1expressiononcirculatingtumourcellsmaybepredictiveofresponsetoregorafenibinpatientsdiagnosedwithchemorefractorymetastaticcolorectalcancer
AT giuseppecimino pdl1expressiononcirculatingtumourcellsmaybepredictiveofresponsetoregorafenibinpatientsdiagnosedwithchemorefractorymetastaticcolorectalcancer
AT gianpaolospinelli pdl1expressiononcirculatingtumourcellsmaybepredictiveofresponsetoregorafenibinpatientsdiagnosedwithchemorefractorymetastaticcolorectalcancer
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