Blockade of Cd40-Cd154 Interferes with Human T cell Engraftment in Scid Mice

Antibodies to the ligand for CD40 (CD154) have been shown to exert profound effects on the development of cell-mediated immune responses in mice. The present study shows that an antibody to human CD154 (hCD40L) inhibits in vivo Tetanus toxoid (TT) specific secondary antibody responses in hu-PBL-scid...

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Main Authors: Teresa M. Foy, Melissa Mcilraith, Sally R. Masters, Jonathan J. Dunn, Aldo A. Rossini, Leonard D. Shultz, Ruth Ann M. Hesselton, Eric J. Wagar, Peter E. Lipsky, Randolph J. Noelle, Dale L. Greiner
Format: Article
Language:English
Published: SAGE Publishing 1998-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979800700105