Exploration of changes in spatial chondrocyte organisation in human osteoarthritic cartilage by means of 3D imaging

Abstract Using two-dimensional top-down view microscopy, researchers have recently described chondrocytes as being spatially arranged in distinct patterns such as strings, double strings, and small and large clusters. Because of the seeming association of these changes with tissue degeneration, they...

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Bibliographic Details
Main Authors: Marina Danalache, Kevin Ralf Beutler, Bernd Rolauffs, Julius Michael Wolfgart, Florian Christof Bonnaire, Stefan Fischer, Imke Greving, Ulf Krister Hofmann
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89582-w