Pharmacokinetic Parameters of Quinine in Healthy Subjects and in Patients with Uncomplicated Malaria in Nigeria: Analysis of Data using a Population Approach

Pharmacokinetic Parameters of Quinine in Healthy Subjects and in Patients with Uncomplicated Malaria in Nigeria: Analysis of Data using a Population Approach

ABSTRACT: Background: The varied disposition of the antimalarial quinine partly explains its poor tolerance and toxicity in humans. Objective: Using a population approach, the disposition of quinine in healthy subjects and patients with acute uncomplicated symptomatic malaria from Nigeria was re-ex...

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Bibliographic Details
Main Authors: Ayorinde Adehin, PhD, Sharon I. Igbinoba, PhD, Julius O. Soyinka, PhD, Cyprian O. Onyeji, PhD, Chinedum P. Babalola, PhD, Oluseye O. Bolaji, PhD
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Current Therapeutic Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X19300165

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