Effect of Organic Solvents and Biologically Relevant Ions on the Light-Induced DNA Cleavage by Pyrene and Its Amino and Hydroxy Derivatives

Abstract: Polycyclic aromatic hydrocarbons (PAHs) are a class of carcinogenic compounds that are both naturally and artificially produced. Many PAHs are pro-carcinogens that require metabolic activation. Recently, it has been shown that PAH can induce DNA single strand cleavage and formation of PAH-...

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Bibliographic Details
Main Authors: Hongtao Yu, Peter P. N. Fu, Huey-Min Hwang, Gernerique Stewart, Shuguang Wang, Shiming Dong
Format: Article
Language:English
Published: MDPI AG 2002-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/3/9/937/