Quantifying Changes in the Cellular Thiol-Disulfide Status during Differentiation of B Cells into Antibody-Secreting Plasma Cells

Quantifying Changes in the Cellular Thiol-Disulfide Status during Differentiation of B Cells into Antibody-Secreting Plasma Cells

Plasma cells produce and secrete massive amounts of disulfide-containing antibodies. To accommodate this load on the secretory machinery, the differentiation of resting B cells into antibody-secreting plasma cells is accompanied by a preferential expansion of the secretory compartments of the cells...

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Bibliographic Details
Main Authors:	Rosa E. Hansen, Mieko Otsu, Ineke Braakman, Jakob R. Winther
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	International Journal of Cell Biology
Online Access:	http://dx.doi.org/10.1155/2013/898563

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