Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli
Resistance to one antibiotic can in some cases increase susceptibility to other antibiotics. Here, Podnecky et al. study these collateral responses in E. coli clinical isolates and show that efflux-related resistance mechanisms and relative fitness of the strains are principal contributors to this p...
Main Authors: | Nicole L. Podnecky, Elizabeth G. A. Fredheim, Julia Kloos, Vidar Sørum, Raul Primicerio, Adam P. Roberts, Daniel E. Rozen, Ørjan Samuelsen, Pål J. Johnsen |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-09-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-06143-y |
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