Comparison of the Diagnostic Performance of qPCR, Sanger Sequencing, and Whole-Genome Sequencing in Determining Clarithromycin and Levofloxacin Resistance in Helicobacter pylori

Comparison of the Diagnostic Performance of qPCR, Sanger Sequencing, and Whole-Genome Sequencing in Determining Clarithromycin and Levofloxacin Resistance in Helicobacter pylori

Helicobacter pylori antibiotic resistance is increasing worldwide, emphasizing the urgent need for more rapid resistance detection prior to the administration of H. pylori eradication regimens. Macrolides and fluoroquinolones are widely used to treat H. pylori. In this study, we aimed to compare the...

Full description

Bibliographic Details
Main Authors: Konrad Egli, Karoline Wagner, Peter M Keller, Lorenz Risch, Martin Risch, Thomas Bodmer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Helicobacter pylori
direct detection in gastric biopsies
(quantitative) real-time PCR
phenotypic drug resistance
23S rDNA gene
gyrA
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.596371/full

Similar Items

Similar Items