Optimizing expression of the pregnancy malaria vaccine candidate, VAR2CSA in <it>Pichia pastoris</it>

Optimizing expression of the pregnancy malaria vaccine candidate, VAR2CSA in <it>Pichia pastoris</it>

<p>Abstract</p> <p>Background</p> <p>VAR2CSA is the main candidate for a vaccine against pregnancy-associated malaria, but vaccine development is complicated by the large size and complex disulfide bonding pattern of the protein. Recent X-ray crystallographic informatio...

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Bibliographic Details
Main Authors: Narum David L, Gose Severin O, Cartwright Megan M, Hathaway Marianne J, Avril Marion, Smith Joseph D
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/8/1/143

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