Alpha7 nAChR Expression Is Correlated with Arthritis Development and Inhibited by Sinomenine in Adjuvant-Induced Arthritic Rats

Sinomenine (SIN) is the active ingredient of the Chinese herb Sinomenium acutum that has been used to treat rheumatoid arthritis (RA) for about 30 years in China. Marked expression of the alpha7 nicotinic acetylcholine receptor (α7nAChR) in the joint synovium of RA patients suggested a relationship...

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Bibliographic Details
Main Authors: Chong Peng, Qing-ping Shi, Jia-yan Liu, Yan-jun Lv, Jing Li, Lang Yi, Sha-sha Bai, Liang Liu, Pei-xun Wang, Hua Zhou, Ke-er Huang, Yan Dong
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2019/3759304