The ketogenic diet raises brain oxygen levels, attenuates postictal hypoxia, and protects against learning impairments

The ketogenic diet raises brain oxygen levels, attenuates postictal hypoxia, and protects against learning impairments

Objectives: A prolonged vasoconstriction/hypoperfusion/hypoxic event follows self-terminating focal seizures. The ketogenic diet (KD) has demonstrated efficacy as a metabolic treatment for intractable epilepsy and other disorders but its effect on local brain oxygen levels is completely unknown. Thi...

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Bibliographic Details
Main Authors: Renaud C. Gom, Dhyey Bhatt, Bianca R. Villa, Antis G. George, Alexander W. Lohman, Richelle Mychasiuk, Jong M. Rho, G. Campbell Teskey
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Neurobiology of Disease
Subjects:
Seizure
Oxygen
Ketones
Blood flow
Learning
β-Hydroxybutyrate
Online Access:http://www.sciencedirect.com/science/article/pii/S096999612100084X

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