Computer-Aided Drug Design Using Sesquiterpene Lactones as Sources of New Structures with Potential Activity against Infectious Neglected Diseases

Computer-Aided Drug Design Using Sesquiterpene Lactones as Sources of New Structures with Potential Activity against Infectious Neglected Diseases

This review presents an survey to the biological importance of sesquiterpene lactones (SLs) in the fight against four infectious neglected tropical diseases (NTDs)—leishmaniasis, schistosomiasis, Chagas disease, and sleeping sickness—as alternatives to the current chemotherapies that display several...

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Bibliographic Details
Main Authors: Chonny Herrera Acevedo, Luciana Scotti, Mateus Feitosa Alves, Margareth De Fátima Formiga Melo Diniz, Marcus Tullius Scotti
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Molecules
Subjects:
computer-aided drug design
neglected tropical diseases
sesquiterpene lactones
secondary metabolites
leishmaniasis
Chagas disease
sleeping sickness
schistosomiasis
QSAR studies
Online Access:http://www.mdpi.com/1420-3049/22/1/79

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