TILs Immunophenotype in Breast Cancer Predicts Local Failure and Overall Survival: Analysis in a Large Radiotherapy Trial with Long-Term Follow-Up

TILs Immunophenotype in Breast Cancer Predicts Local Failure and Overall Survival: Analysis in a Large Radiotherapy Trial with Long-Term Follow-Up

Aim: To determine the prognostic significance of the immunophenotype of tumour-infiltrating lymphocytes (TILs) within a cohort of breast cancer patients with long-term follow-up. Methods: Multiplexed immunofluorescence and automated image analysis were used to assess the expression of CD3, CD8, CD20...

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Bibliographic Details
Main Authors: Ewan Millar, Lois Browne, Iveta Slapetova, Fei Shang, Yuqi Ren, Rachel Bradshaw, Heather Ann Brauer, Sandra O’Toole, Julia Beretov, Renee Whan, Peter H. Graham
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
tumour infiltrating lymphocytes (TILs)
immunophenotype
prognosis
breast cancer
Online Access:https://www.mdpi.com/2072-6694/12/9/2365

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