Next-generation sequencing to monitor the spread of antimicrobial resistance

Abstract Next-generation sequencing is increasingly being used to monitor current and historic events related to the emergence and spread of antimicrobial resistance. In a recent publication, researchers analyzed the rise of methicillin-resistant Staphylococcus aureus in the 1960s, emphasizing that...

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Bibliographic Details
Main Author: Michael Otto
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Genome Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13073-017-0461-x
Description
Summary:Abstract Next-generation sequencing is increasingly being used to monitor current and historic events related to the emergence and spread of antimicrobial resistance. In a recent publication, researchers analyzed the rise of methicillin-resistant Staphylococcus aureus in the 1960s, emphasizing that adaptations conferring antibiotic resistance might pre-date the introduction of novel antibiotic derivatives. Other researchers have evaluated the role of transmission within a healthcare network, using the example of extended-spectrum beta-lactamase-resistant Escherichia coli. Please see related Genome Biology Research article: www.dx.doi.org/10.1186/s13059-017-1252-9 and Genome Medicine Research article: www.dx.doi.org/10.1186/s13073-017-0457-6
ISSN:1756-994X