Extracorporeal membrane oxygenator as a bridge to successful surgical repair of bronchopleural fistula following bilateral sequential lung transplantation: a case report and review of literature

<p>Abstract</p> <p>Background</p> <p>Lung transplantation (LTx) is widely accepted as a therapeutic option for end-stage respiratory failure in cystic fibrosis. However, airway complications remain a major cause of morbidity and mortality in these patients, serious airw...

Full description

Bibliographic Details
Main Authors: Machaal Ali, Khasati Noman, Al-Aloul Mohamed, Khan Nouman U, Leonard Colm T, Yonan Nizar
Format: Article
Language:English
Published: BMC 2007-06-01
Series:Journal of Cardiothoracic Surgery
Online Access:http://www.cardiothoracicsurgery.org/content/2/1/28
id doaj-15d2e67c8f164426886b474a4c28136e
record_format Article
spelling doaj-15d2e67c8f164426886b474a4c28136e2020-11-24T22:16:06ZengBMCJournal of Cardiothoracic Surgery1749-80902007-06-01212810.1186/1749-8090-2-28Extracorporeal membrane oxygenator as a bridge to successful surgical repair of bronchopleural fistula following bilateral sequential lung transplantation: a case report and review of literatureMachaal AliKhasati NomanAl-Aloul MohamedKhan Nouman ULeonard Colm TYonan Nizar<p>Abstract</p> <p>Background</p> <p>Lung transplantation (LTx) is widely accepted as a therapeutic option for end-stage respiratory failure in cystic fibrosis. However, airway complications remain a major cause of morbidity and mortality in these patients, serious airway complications like bronchopleural fistula (BPF) are rare, and their management is very difficult.</p> <p>Case presentation</p> <p>A 47-year-old man with end-stage respiratory failure due to cystic fibrosis underwent bilateral sequential lung transplantation. Severe post-operative bleeding occurred due to dense intrapleural adhesions of the native lungs. He was re-explored and packed leading to satisfactory haemostasis. He developed a bronchopleural fistula on the 14<sup>th </sup>post-operative day. The fistula was successfully repaired using pericardial and intercostal vascular flaps with veno-venous extracorporeal membrane oxygenator (VV-ECMO) support. Subsequently his recovery was uneventful.</p> <p>Conclusion</p> <p>The combination of pedicled intercostal and pericardial flaps provide adequate vascular tissue for sealing a large BPF following LTx. Veno-venous ECMO allows a feasible bridge to recovery.</p> http://www.cardiothoracicsurgery.org/content/2/1/28
collection DOAJ
language English
format Article
sources DOAJ
author Machaal Ali
Khasati Noman
Al-Aloul Mohamed
Khan Nouman U
Leonard Colm T
Yonan Nizar
spellingShingle Machaal Ali
Khasati Noman
Al-Aloul Mohamed
Khan Nouman U
Leonard Colm T
Yonan Nizar
Extracorporeal membrane oxygenator as a bridge to successful surgical repair of bronchopleural fistula following bilateral sequential lung transplantation: a case report and review of literature
Journal of Cardiothoracic Surgery
author_facet Machaal Ali
Khasati Noman
Al-Aloul Mohamed
Khan Nouman U
Leonard Colm T
Yonan Nizar
author_sort Machaal Ali
title Extracorporeal membrane oxygenator as a bridge to successful surgical repair of bronchopleural fistula following bilateral sequential lung transplantation: a case report and review of literature
title_short Extracorporeal membrane oxygenator as a bridge to successful surgical repair of bronchopleural fistula following bilateral sequential lung transplantation: a case report and review of literature
title_full Extracorporeal membrane oxygenator as a bridge to successful surgical repair of bronchopleural fistula following bilateral sequential lung transplantation: a case report and review of literature
title_fullStr Extracorporeal membrane oxygenator as a bridge to successful surgical repair of bronchopleural fistula following bilateral sequential lung transplantation: a case report and review of literature
title_full_unstemmed Extracorporeal membrane oxygenator as a bridge to successful surgical repair of bronchopleural fistula following bilateral sequential lung transplantation: a case report and review of literature
title_sort extracorporeal membrane oxygenator as a bridge to successful surgical repair of bronchopleural fistula following bilateral sequential lung transplantation: a case report and review of literature
publisher BMC
series Journal of Cardiothoracic Surgery
issn 1749-8090
publishDate 2007-06-01
description <p>Abstract</p> <p>Background</p> <p>Lung transplantation (LTx) is widely accepted as a therapeutic option for end-stage respiratory failure in cystic fibrosis. However, airway complications remain a major cause of morbidity and mortality in these patients, serious airway complications like bronchopleural fistula (BPF) are rare, and their management is very difficult.</p> <p>Case presentation</p> <p>A 47-year-old man with end-stage respiratory failure due to cystic fibrosis underwent bilateral sequential lung transplantation. Severe post-operative bleeding occurred due to dense intrapleural adhesions of the native lungs. He was re-explored and packed leading to satisfactory haemostasis. He developed a bronchopleural fistula on the 14<sup>th </sup>post-operative day. The fistula was successfully repaired using pericardial and intercostal vascular flaps with veno-venous extracorporeal membrane oxygenator (VV-ECMO) support. Subsequently his recovery was uneventful.</p> <p>Conclusion</p> <p>The combination of pedicled intercostal and pericardial flaps provide adequate vascular tissue for sealing a large BPF following LTx. Veno-venous ECMO allows a feasible bridge to recovery.</p>
url http://www.cardiothoracicsurgery.org/content/2/1/28
work_keys_str_mv AT machaalali extracorporealmembraneoxygenatorasabridgetosuccessfulsurgicalrepairofbronchopleuralfistulafollowingbilateralsequentiallungtransplantationacasereportandreviewofliterature
AT khasatinoman extracorporealmembraneoxygenatorasabridgetosuccessfulsurgicalrepairofbronchopleuralfistulafollowingbilateralsequentiallungtransplantationacasereportandreviewofliterature
AT alaloulmohamed extracorporealmembraneoxygenatorasabridgetosuccessfulsurgicalrepairofbronchopleuralfistulafollowingbilateralsequentiallungtransplantationacasereportandreviewofliterature
AT khannoumanu extracorporealmembraneoxygenatorasabridgetosuccessfulsurgicalrepairofbronchopleuralfistulafollowingbilateralsequentiallungtransplantationacasereportandreviewofliterature
AT leonardcolmt extracorporealmembraneoxygenatorasabridgetosuccessfulsurgicalrepairofbronchopleuralfistulafollowingbilateralsequentiallungtransplantationacasereportandreviewofliterature
AT yonannizar extracorporealmembraneoxygenatorasabridgetosuccessfulsurgicalrepairofbronchopleuralfistulafollowingbilateralsequentiallungtransplantationacasereportandreviewofliterature
_version_ 1725791325832347648