Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules
Human epidermal growth factor receptor type 3 (HER3) is an emerging therapeutic target in several malignancies. To select potential responders to HER3-targeted therapy, radionuclide molecular imaging of HER3 expression using affibody molecules could be performed. Due to physiological expression of H...
Main Authors: | Sara S. Rinne, Tianqi Xu, Charles Dahlsson Leitao, Stefan Ståhl, John Löfblom, Anna Orlova, Vladimir Tolmachev, Anzhelika Vorobyeva |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-02-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/4/1312 |
Similar Items
-
Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs
by: Mohamed Altai, et al.
Published: (2018-10-01) -
Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of 68Ga-Labeled Tracers
by: Charles Dahlsson Leitao, et al.
Published: (2019-03-01) -
Tumour Targeting using Radiolabelled Affibody Molecules : Influence of Labelling Chemistry
by: Altai, Mohamed
Published: (2014) -
Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules
by: Sara S. Rinne, et al.
Published: (2020-03-01) -
Development of Affibody molecules for radionuclide molecular imaging and therapy of cancer
by: Honarvar, Hadis
Published: (2016)