Netrin-1/DCC Signaling Differentially Regulates the Migration of Pax7, Nkx6.1, Irx2, Otp, and Otx2 Cell Populations in the Developing Interpeduncular Nucleus

Netrin-1/DCC Signaling Differentially Regulates the Migration of Pax7, Nkx6.1, Irx2, Otp, and Otx2 Cell Populations in the Developing Interpeduncular Nucleus

The interpeduncular nucleus (IPN) is a hindbrain structure formed by three main subdivisions, the prodromal (Pro) domain located at the isthmus (Ist), and the rostral and caudal interpeduncular domains (IPR, IPC) within rhombomere 1 (r1). Various cell populations can be detected in the IPN through t...

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Bibliographic Details
Main Authors: Isabel M. García-Guillén, Antonia Alonso, Nicanor Morales-Delgado, Belén Andrés, Luis Puelles, Guillermina López-Bendito, Faustino Marín, Pilar Aroca
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
neuronal tangential migration
axon guidance
Netrin1
DCC
transcription factors
rhombomeres
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.588851/full

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