Current views on the genetic landscape and management of variant acute promyelocytic leukemia

Current views on the genetic landscape and management of variant acute promyelocytic leukemia

Abstract Acute promyelocytic leukemia (APL) is characterized by the accumulation of promyelocytes in bone marrow. More than 95% of patients with this disease belong to typical APL, which express PML-RARA and are sensitive to differentiation induction therapy containing all-trans retinoic acid (ATRA)...

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Bibliographic Details
Main Authors: Xiang Zhang, Jiewen Sun, Wenjuan Yu, Jie Jin
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Biomarker Research
Subjects:
Variant acute promyelocytic leukemia
Genetic landscape
Management
Online Access:https://doi.org/10.1186/s40364-021-00284-x

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