Three-Dimensional Imaging of Pulmonary Fibrotic Foci at the Alveolar Scale Using Tissue-Clearing Treatment with Staining Techniques of Extracellular Matrix

Idiopathic pulmonary fibrosis is a progressive, chronic lung disease characterized by the accumulation of extracellular matrix proteins, including collagen and elastin. Imaging of extracellular matrix in fibrotic lungs is important for evaluating its pathological condition as well as the distributio...

Full description

Bibliographic Details
Main Authors: Kohei Togami, Hiroaki Ozaki, Yuki Yumita, Anri Kitayama, Hitoshi Tada, Sumio Chono
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2020/8815231