Non-uniform self-assembly: On the anisotropic architecture of α-synuclein supra-fibrillar aggregates
Abstract Although the function of biopolymer hydrogels in nature depends on structural anisotropy at mesoscopic length scales, the self-assembly of such anisotropic structures in vitro is challenging. Here we show that fibrils of the protein α-synuclein spontaneously self-assemble into structurally...
Main Authors: | Slav A. Semerdzhiev, Volodymyr V. Shvadchak, Vinod Subramaniam, Mireille M. A. E. Claessens |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-06532-1 |
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