Cyanidin-3-galactoside from Aronia melanocarpa ameliorates PM10 induced pulmonary injury by modulating M1/M2 macrophage polarization and NRF2/Sirt1 MAPK signaling

Cyanidin-3-galactoside from Aronia melanocarpa ameliorates PM10 induced pulmonary injury by modulating M1/M2 macrophage polarization and NRF2/Sirt1 MAPK signaling

Aronia melanocarpa is rich in anthocyanins that exert many beneficial effects. We extracted cyanidin-3-galactoside (C3G), the most abundant anthocyanin in Aronia melanocarpa, and applied to PM10-exposed mice to investigate anti-inflammatory properties and underlying cellular mechanism. Administratio...

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Bibliographic Details
Main Authors: Yanmin Cui, Yang Lin, Xianjun Meng, Jingxuan Ma, Haotian Deng, Xia Liu, Xinyuan He, Jin Zhao
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Journal of Functional Foods
Subjects:
Aronia melanocarpa
Cyanidin-3-galactoside
PM10
Pulmonary inflammation
Macrophage polarization
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621000128

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http://www.sciencedirect.com/science/article/pii/S1756464621000128

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