Oseltamivir (Tamiflu)-induced bilateral acute angle closure glaucoma and transient myopia

• Main Authors: Ji Woong Lee, Ji Eun Lee, Hee Young Choi, Jong Soo Lee
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2014-01-01
• Series: Indian Journal of Ophthalmology
• Subjects: Malignant glaucoma; pseudophakic; surgical management; zonulo-hyaloido-vitrectomy; Automated retinal imaging; diabetic retinopathy; screening; Low vision; low vision aids; quality of life; Children; congenital cataract; hydrophobic acrylic intraocular lens; intraocular lens implantation; myopic shift; polymethyl methacrylate; Cost-effectiveness; glaucoma; pharmacoeconomics; External limiting membrane; macular hole; predictors; Optic nerve head drusen; optical coherence tomography; papilledema; pseudopapilloedema; Crowding; logMAR chart; refractive error; visual acuity; Acute retinal pigment epithelitis; multifocal electroretinogram; Anterior chamber; intraocular parasite; Linguatula serrata (tongue worm); subluxated lens; vitrectomy; Carbonic anhydrase inhibitor; Danon disease; ERG; retinal disease; SD-OCT; Levodopa; occlusion amblyopia; reverse amblyopia; Acute angle closure glaucoma; ciliochoroidal effusion; oseltamivir; transient myopia
• Online Access: http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=12;spage=1165;epage=1167;aulast=Lee

A 27-year-old woman developed bilateral acute angle closure glaucoma (AACG) and transient myopia after taking oseltamivir for four days. On the fourth day, she received systemic and topical intraocular pressure (IOP)-lowering agents, and IOP decreased in both eyes. However, her visual acuity was unchanged. A myopic shift of -5.25 D OD and -5.0 D OS was estimated to have occurred in the acute phase. A-scan ultrasonography and Pentacam showed markedly shallow anterior chambers and increased lens thickness. Ultrasound biomicroscopy revealed an annular ciliochoroidal effusion with forward displacement of the lens-iris diaphragm. Ciliochoroidal effusion and transient myopia were resolved after discontinuation of oseltamivir.