Fluorescent antibiotics for real-time tracking of pathogenic bacteria

Fluorescent antibiotics for real-time tracking of pathogenic bacteria

The harm of pathogenic bacteria to humans has promoted extensive research on physiological processes of pathogens, such as the mechanism of bacterial infection, antibiotic mode of action, and bacterial antimicrobial resistance. Most of these processes can be better investigated by timely tracking of...

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Bibliographic Details
Main Authors: Lu Miao, Weiwei Liu, Qinglong Qiao, Xiaolian Li, Zhaochao Xu
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Fluorescent antibiotics
Live-cell tracking
Fluorophore
Pathogenic bacteria
Fluorescent imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177920310595
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spelling doaj-156fafad32dd423ab844c8cc168305452021-04-02T15:39:30ZengElsevierJournal of Pharmaceutical Analysis2095-17792020-10-01105444451Fluorescent antibiotics for real-time tracking of pathogenic bacteriaLu Miao0Weiwei Liu1Qinglong Qiao2Xiaolian Li3Zhaochao Xu4CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, ChinaCAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China; State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, 116012, ChinaCAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, ChinaState Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, 116012, China; Corresponding author.CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China; Corresponding author.The harm of pathogenic bacteria to humans has promoted extensive research on physiological processes of pathogens, such as the mechanism of bacterial infection, antibiotic mode of action, and bacterial antimicrobial resistance. Most of these processes can be better investigated by timely tracking of fluorophore-derived antibiotics in living cells. In this paper, we will review the recent development of fluorescent antibiotics featuring the conjugation with various fluorophores, and focus on their applications in fluorescent imaging and real-time detection for various physiological processes of bacteria in vivo.http://www.sciencedirect.com/science/article/pii/S2095177920310595Fluorescent antibioticsLive-cell trackingFluorophorePathogenic bacteriaFluorescent imaging
collection DOAJ
language English
format Article
sources DOAJ
author Lu Miao
Weiwei Liu
Qinglong Qiao
Xiaolian Li
Zhaochao Xu
spellingShingle Lu Miao
Weiwei Liu
Qinglong Qiao
Xiaolian Li
Zhaochao Xu
Fluorescent antibiotics for real-time tracking of pathogenic bacteria
Journal of Pharmaceutical Analysis
Fluorescent antibiotics
Live-cell tracking
Fluorophore
Pathogenic bacteria
Fluorescent imaging
author_facet Lu Miao
Weiwei Liu
Qinglong Qiao
Xiaolian Li
Zhaochao Xu
author_sort Lu Miao
title Fluorescent antibiotics for real-time tracking of pathogenic bacteria
title_short Fluorescent antibiotics for real-time tracking of pathogenic bacteria
title_full Fluorescent antibiotics for real-time tracking of pathogenic bacteria
title_fullStr Fluorescent antibiotics for real-time tracking of pathogenic bacteria
title_full_unstemmed Fluorescent antibiotics for real-time tracking of pathogenic bacteria
title_sort fluorescent antibiotics for real-time tracking of pathogenic bacteria
publisher Elsevier
series Journal of Pharmaceutical Analysis
issn 2095-1779
publishDate 2020-10-01
description The harm of pathogenic bacteria to humans has promoted extensive research on physiological processes of pathogens, such as the mechanism of bacterial infection, antibiotic mode of action, and bacterial antimicrobial resistance. Most of these processes can be better investigated by timely tracking of fluorophore-derived antibiotics in living cells. In this paper, we will review the recent development of fluorescent antibiotics featuring the conjugation with various fluorophores, and focus on their applications in fluorescent imaging and real-time detection for various physiological processes of bacteria in vivo.
topic Fluorescent antibiotics
Live-cell tracking
Fluorophore
Pathogenic bacteria
Fluorescent imaging
url http://www.sciencedirect.com/science/article/pii/S2095177920310595
work_keys_str_mv AT lumiao fluorescentantibioticsforrealtimetrackingofpathogenicbacteria
AT weiweiliu fluorescentantibioticsforrealtimetrackingofpathogenicbacteria
AT qinglongqiao fluorescentantibioticsforrealtimetrackingofpathogenicbacteria
AT xiaolianli fluorescentantibioticsforrealtimetrackingofpathogenicbacteria
AT zhaochaoxu fluorescentantibioticsforrealtimetrackingofpathogenicbacteria
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