HSV-1-Specific IgG<sub>3</sub> Titers Correlate with Brain Cortical Thinning in Individuals with Mild Cognitive Impairment and Alzheimer’s Disease

HSV-1-Specific IgG<sub>3</sub> Titers Correlate with Brain Cortical Thinning in Individuals with Mild Cognitive Impairment and Alzheimer’s Disease

Repeated reactivations of latent herpes simplex virus type-1 (HSV-1) in the central nervous system (CNS) may contribute to neurodegeneration in Alzheimer’s disease (AD) patients. Immune response is a key element for the control of viral reactivation. HSV-1 uses a number of strategies to evade immune...

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Bibliographic Details
Main Authors: Roberta Mancuso, Monia Cabinio, Simone Agostini, Francesca Baglio, Mario Clerici
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Vaccines
Subjects:
Alzheimer’s disease
HSV-1
HSV-1-IgG subclasses
IgG<sub>3</sub>
mild cognitive impairment
magnetic resonance imaging (MRI)
Online Access:https://www.mdpi.com/2076-393X/8/2/255

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