Identification of ARGLU1 as a potential therapeutic target for gastric cancer based on genome-wide functional screening data

Identification of ARGLU1 as a potential therapeutic target for gastric cancer based on genome-wide functional screening data

Background: Due to the molecular mechanism complexity and heterogeneity of gastric cancer (GC), mechanistically interpretable biomarkers were required for predicting prognosis and discovering therapeutic targets for GC patients. Methods: Based on a total of 824 GC-specific fitness genes from the Pro...

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Bibliographic Details
Main Authors: Fangyuan Li, Jianfang Li, Junxian Yu, Tao Pan, Beiqin Yu, Qingqing Sang, Wentao Dai, Junyi Hou, Chao Yan, Mingde Zang, Zhenggang Zhu, Liping Su, Yuan-Yuan Li, Bingya Liu
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:EBioMedicine
Subjects:
Gastric cancer
Prognostic model
Therapeutic target
ARGLU1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421002292

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http://www.sciencedirect.com/science/article/pii/S2352396421002292

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