B Cell Depletion: Rituximab in Glomerular Disease and Transplantation

B cells play a central role in the pathogenesis of many autoimmune diseases. Selective targeting can be achieved with the use of the monoclonal antibody rituximab. In addition to being a drug for non-Hodgkin's lymphoma, rituximab is also an FDA-approved treatment for refractory rheumatoid arthr...

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Bibliographic Details
Main Authors: S. Marinaki, C. Skalioti, J.N. Boletis
Format: Article
Language:English
Published: Karger Publishers 2013-12-01
Series:Nephron Extra
Subjects:
Online Access:http://www.karger.com/Article/FullText/356050