The OPN Gene Polymorphism Confers the Susceptibility and Response to Ara-C Based Chemotherapy in Chinese AML Patients

The OPN Gene Polymorphism Confers the Susceptibility and Response to Ara-C Based Chemotherapy in Chinese AML Patients

Aim: To investigate the possible association between the Osteopontin (OPN) gene polymorphisms and the susceptibility and chemotherapy response of acute myeloid leukemia patients. Methods: A total of 381 patients with de nova AML and 430 healthy controls were enrolled. All patients received Ara-C-bas...

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Bibliographic Details
Main Authors: Rong Zhang, Wei Yang, Ying Chun Li, Guo Jun Zhang, Kun Yao, Rong Hu, Bin Wu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Osteopontin
Acute myeloid leukemia
Chemotherapy
Polymorphism
Susceptibility
Online Access:http://www.karger.com/Article/FullText/369685

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