Targeting the Fibroblast Growth Factor Receptor (FGFR) in Advanced Cholangiocarcinoma: Clinical Trial Progress and Future Considerations

Targeting the Fibroblast Growth Factor Receptor (FGFR) in Advanced Cholangiocarcinoma: Clinical Trial Progress and Future Considerations

Landmark molecular profiling efforts have identified multiple targetable alterations in cholangiocarcinoma. Among the molecular-driven subsets of cholangiocarcinoma, targeting the fibroblast growth factor receptor (FGFR) has shown promise and represents the first targeted therapy to be approved in t...

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Bibliographic Details
Main Authors: Patrick C. Lee, Andrew Hendifar, Arsen Osipov, May Cho, Daneng Li, Jun Gong
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
cholangiocarcinoma
fibroblast growth factor receptor (FGFR)
pemigatinib
infigratinib
derazantinib
debio 1347
Online Access:https://www.mdpi.com/2072-6694/13/7/1706

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