Enhanced bioactivity of GO–Fe3O4 nanocomposite against pathogenic bacterial strains

Rajni Singh,1 Mony Sreedharan Smitha,1 Stalin Karuppiah,2 Surinder P Singh2 1Amity Institute of Microbial Biotechnology, Amity University, Noida, Uttar Pradesh, 2CSIR-National Physical Laboratory, New Delhi, Delhi, India Abstract: GO with –OH, –CHO, –CO, –CO...

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Bibliographic Details
Main Authors: Singh R, Smitha MS, Karuppiah S, Singh SP
Format: Article
Language:English
Published: Dove Medical Press 2018-03-01
Series:International Journal of Nanomedicine
Subjects:
Online Access:https://www.dovepress.com/enhanced-bioactivity-of-go-fe3o4-nanocomposite-against-pathogenic-bact-peer-reviewed-article-IJN
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Summary:Rajni Singh,1 Mony Sreedharan Smitha,1 Stalin Karuppiah,2 Surinder P Singh2 1Amity Institute of Microbial Biotechnology, Amity University, Noida, Uttar Pradesh, 2CSIR-National Physical Laboratory, New Delhi, Delhi, India Abstract: GO with –OH, –CHO, –CO, –COOH, and epoxide groups is considered more suitable than other commonly used materials for biomedical applications. The presence of –CO, –CHO, and –OH groups renders the easy functionalization of GO by biomolecules and drugs. Therefore, in this study, we designed a multifunctional GO–Fe3O4 nanocomposite and investigated its bactericidal activity against different bacterial strains with an evaluation of percentage inhibition. Our results revealed the potential of GO–Fe3O4 nanocomposites as an effective bactericidal, which can be used for dynamic applications in medical devices and food and other industries. Keywords: graphene oxide, GO nanocomposites, GO–Fe3O4, pathogenic strains, antibacterial
ISSN:1178-2013