Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates

Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates

Aβ is the toxic amyloid polypeptide responsible for Alzheimer’s disease (AD). Prevention and elimination of the Aβ misfolded aggregates are the promising therapeutic strategies for the AD treatments. Gammabody, the Aβ-Specific Single-domain (VH) antibody, recogni...

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Bibliographic Details
Main Authors: Mingzhen Zhang, Jie Zheng, Ruth Nussinov, Buyong Ma
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Antibodies
Subjects:
single-domain antibodies
Aβ peptide
amyloid antibody
Alzheimer’s disease
antibody recognition
Online Access:http://www.mdpi.com/2073-4468/7/3/25

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