Post-traumatic exogenous endophthalmitis caused by Nocardia farcinica

• Main Authors: Marie Česká Burdová, Kateřina Donátová, Gabriela Mahelková, Vanda Chrenková, Dagmar Dotřelová
• Format: Article
• Language: English
• Published: SpringerOpen 2021-06-01
• Series: Journal of Ophthalmic Inflammation and Infection
• Subjects: Nocardia farcinica; Post-traumatic endophthalmitis
• Online Access: https://doi.org/10.1186/s12348-021-00245-3

Abstract A case report of post-traumatic exogenous endophthalmitis caused by Nocardia farcinica, including treatment procedures, microbiology examination, and systemic medications. A 23-year-old male suffered a penetrating corneal injury that was treated with sutures. On the thirteenth day after the final suture was removed, an anterior uveitis developed and progressed to whitish, plump, nodular, and tufted exudates within the anterior chamber over the next 10 days; this led to an indication for intraocular surgery. Anterior chamber lavage and resection of solid fibrinous exudates (using a vitrectomy knife) for a complete microbiological examination were performed. Nocardia farcinica was identified. Systemic medications were chosen according to sensitivity, and a fixed combination of sulfamethoxazole 400 mg/trimethoprim 80 mg was administered long-term (months). In this case, accurate, early detection of an atypical infectious agent and determination of its sensitivity to antibiotic treatment enabled effective treatment that achieved the best functional and anatomical results under the circumstances.