The first preparative solution phase synthesis of melanotan II

The first preparative solution phase synthesis of melanotan II

Melanotan II is a synthetic cyclic heptapeptide used to prevent a sunlight-induced skin cancer by stimulating the skin tanning process. In this paper we report the first solution phase synthesis of the title compound. The hexapeptide sequence has been assembled by [(2+2)+1+1] scheme. After removing...

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Bibliographic Details
Main Authors: Vladimir V. Ryakhovsky, Georgy A. Khachiyan, Nina F. Kosovova, Elena F. Isamiddinova, Andrey S. Ivanov
Format: Article
Language:English
Published: Beilstein-Institut 2008-10-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
melanotan II
solution phase synthesis
peptide synthesis
Online Access:https://doi.org/10.3762/bjoc.4.39

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