HLA-B27 and human β2-microglobulin affect the gut microbiota of transgenic rats.

HLA-B27 and human β2-microglobulin affect the gut microbiota of transgenic rats.

The HLA-B27 gene is a major risk factor for clinical diseases including ankylosing spondylitis, acute anterior uveitis, reactive arthritis, and psoriatic arthritis, but its mechanism of risk enhancement is not completely understood. The gut microbiome has recently been shown to influence several HLA...

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Bibliographic Details
Main Authors: Phoebe Lin, Mary Bach, Mark Asquith, Aaron Y Lee, Lakshmi Akileswaran, Patrick Stauffer, Sean Davin, Yuzhen Pan, Eric D Cambronne, Martha Dorris, Justine W Debelius, Christian L Lauber, Gail Ackermann, Yoshiki V Baeza, Tejpal Gill, Rob Knight, Robert A Colbert, Joel D Taurog, Russell N Van Gelder, James T Rosenbaum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4139385?pdf=render

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