Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability
The epithelial-mesenchymal transition (EMT) is a dynamic process that plays important roles in cancer progression and metastasis. Here, the authors characterize a non-linear hysteretic response of E-cadherin repression during TGFβ-induced EMT that is controlled by the strength of the miR-200s/ZEBs n...
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Bibliographic Details
| Main Authors: |
Toni Celià-Terrassa,
Caleb Bastian,
Daniel D. Liu,
Brian Ell,
Nicole M. Aiello,
Yong Wei,
Jose Zamalloa,
Andres M. Blanco,
Xiang Hang,
Dmitriy Kunisky,
Wenyang Li,
Elizabeth D. Williams,
Herschel Rabitz,
Yibin Kang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2018-11-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-07538-7
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