| Summary: | Vukičević and Gasperov introduced the concept of 148 discrete Adriatic indices in 2010. These indices showed good predictive properties against the testing sets of the International Academy of Mathematical Chemistry. Among these indices, twenty indices were taken as beneficial predictors of physicochemical properties. The inverse sum indeg index denoted by ISIGk of Gk is a notable predictor of total surface area for octane isomers and is presented as ISIGk=∑gkgk′∈EGkdGkgkdGkgk′/dGkgk+dGkgk′, where dGkgk represents the degree of gk∈VGk. In this paper, we determine sharp bounds for ISI index of graph operations, including the Cartesian product, tensor product, strong product, composition, disjunction, symmetric difference, corona product, Indu–Bala product, union of graphs, double graph, and strong double graph.
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