Affective and cognitive behavior in the alpha-galactosidase A deficient mouse model of Fabry disease.

Affective and cognitive behavior in the alpha-galactosidase A deficient mouse model of Fabry disease.

Fabry disease is an X-linked inherited lysosomal storage disorder with intracellular accumulation of globotriaosylceramide (Gb3) due to α-galactosidase A (α-Gal A) deficiency. Fabry patients frequently report of anxiety, depression, and impaired cognitive function. We characterized affective and cog...

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Bibliographic Details
Main Authors:	Lukas Hofmann, Franziska Karl, Claudia Sommer, Nurcan Üçeyler
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2017-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC5491260?pdf=render

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