Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation.

Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation.

Mechanisms behind how the immune system signals to the brain in response to systemic inflammation are not fully understood. Transgenic mice expressing Cre recombinase specifically in the hematopoietic lineage in a Cre reporter background display recombination and marker gene expression in Purkinje n...

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Bibliographic Details
Main Authors: Kirsten Ridder, Sascha Keller, Maria Dams, Anne-Kathleen Rupp, Jessica Schlaudraff, Domenico Del Turco, Julia Starmann, Jadranka Macas, Darja Karpova, Kavi Devraj, Candan Depboylu, Britta Landfried, Bernd Arnold, Karl H Plate, Günter Höglinger, Holger Sültmann, Peter Altevogt, Stefan Momma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4043485?pdf=render

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