Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain
Samsonova et al. show a cooperative association of Lin28 and YB-1 for their target mRNA through their cold-shock domain, which is a conserved β-barrel structure that binds to single-stranded RNA. This study suggests that the association of Lin28 with YB-1 in mRNPs may contribute to the translational...
Full description
Bibliographic Details
| Main Authors: |
Anastasiia Samsonova,
Krystel El Hage,
Bénédicte Desforges,
Vandana Joshi,
Marie-Jeanne Clément,
Guillaume Lambert,
Hélène Henrie,
Nicolas Babault,
Pierrick Craveur,
Rachid C. Maroun,
Emilie Steiner,
Ahmed Bouhss,
Alexandre Maucuer,
Dmitry N. Lyabin,
Lev P. Ovchinnikov,
Loic Hamon,
David Pastré |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Publishing Group
2021-03-01
|
|---|
| Series: | Communications Biology
|
|---|
| Online Access: | https://doi.org/10.1038/s42003-021-01862-3
|
|---|
