Systemic Administration of Insulin Receptor Antagonist Results in Endothelial and Perivascular Adipose Tissue Dysfunction in Mice

Systemic Administration of Insulin Receptor Antagonist Results in Endothelial and Perivascular Adipose Tissue Dysfunction in Mice

Hyperglycemia linked to diabetes results in endothelial dysfunction. In the present work, we comprehensively characterized effects of short-term hyperglycemia induced by administration of an insulin receptor antagonist, the S961 peptide, on endothelium and perivascular adipose tissue (PVAT) in mice....

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Bibliographic Details
Main Authors: Bartosz Proniewski, Anna Bar, Anna Kieronska-Rudek, Joanna Suraj-Prażmowska, Elżbieta Buczek, Krzysztof Czamara, Zuzanna Majka, Izabela Czyzynska-Cichon, Grzegorz Kwiatkowski, Karolina Matyjaszczyk-Gwarda, Stefan Chlopicki
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
endothelial function
magnetic resonance imaging
perivascular adipose tissue
insulin receptor antagonist
Online Access:https://www.mdpi.com/2073-4409/10/6/1448

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https://www.mdpi.com/2073-4409/10/6/1448

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