The role of surfactant in asthma
<p>Abstract</p> <p>Pulmonary surfactant is a unique mixture of lipids and surfactant-specific proteins that covers the entire alveolar surface of the lungs. Surfactant is not restricted to the alveolar compartment; it also reaches terminal conducting airways and is present in up...
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| Format: | Article |
| Language: | English |
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BMC
2002-01-01
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| Series: | Respiratory Research |
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| Online Access: | http://dx.doi.org/10.1186/rr176 |
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Article |
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doaj-15160a768c7b4598905fa823ecba87f02020-11-25T00:19:08ZengBMCRespiratory Research1465-99212002-01-01314The role of surfactant in asthmaHohlfeld Jens<p>Abstract</p> <p>Pulmonary surfactant is a unique mixture of lipids and surfactant-specific proteins that covers the entire alveolar surface of the lungs. Surfactant is not restricted to the alveolar compartment; it also reaches terminal conducting airways and is present in upper airway secretions. While the role of surfactant in the alveolar compartment has been intensively elucidated both in health and disease states, the possible role of surfactant in the airways requires further research. This review summarizes the current knowledge on surfactant functions regarding the airway compartment and highlights the impact of various surfactant components on allergic inflammation in asthma.</p> http://dx.doi.org/10.1186/rr176airwaysallergyasthmainnate immunitysurfactant function |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Hohlfeld Jens |
| spellingShingle |
Hohlfeld Jens The role of surfactant in asthma Respiratory Research airways allergy asthma innate immunity surfactant function |
| author_facet |
Hohlfeld Jens |
| author_sort |
Hohlfeld Jens |
| title |
The role of surfactant in asthma |
| title_short |
The role of surfactant in asthma |
| title_full |
The role of surfactant in asthma |
| title_fullStr |
The role of surfactant in asthma |
| title_full_unstemmed |
The role of surfactant in asthma |
| title_sort |
role of surfactant in asthma |
| publisher |
BMC |
| series |
Respiratory Research |
| issn |
1465-9921 |
| publishDate |
2002-01-01 |
| description |
<p>Abstract</p> <p>Pulmonary surfactant is a unique mixture of lipids and surfactant-specific proteins that covers the entire alveolar surface of the lungs. Surfactant is not restricted to the alveolar compartment; it also reaches terminal conducting airways and is present in upper airway secretions. While the role of surfactant in the alveolar compartment has been intensively elucidated both in health and disease states, the possible role of surfactant in the airways requires further research. This review summarizes the current knowledge on surfactant functions regarding the airway compartment and highlights the impact of various surfactant components on allergic inflammation in asthma.</p> |
| topic |
airways allergy asthma innate immunity surfactant function |
| url |
http://dx.doi.org/10.1186/rr176 |
| work_keys_str_mv |
AT hohlfeldjens theroleofsurfactantinasthma AT hohlfeldjens roleofsurfactantinasthma |
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1725373116775923712 |