Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats

Abstract Hyperoxia-induced lung injury plays a key role in the development of bronchopulmonary dysplasia (BPD), characterized by inflammatory injury and impaired lung development in preterm infants. Although BPD is a predictor of poor neurodevelopmental outcomes, currently it is uncertain how lung i...

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Bibliographic Details
Main Authors: Anum Ali, Ronald Zambrano, Matthew R. Duncan, Shaoyi Chen, Shihua Luo, Huijun Yuan, Pingping Chen, Merline Benny, Augusto Schmidt, Karen Young, Nadine Kerr, Juan Pablo de Rivero Vaccari, Robert W. Keane, W. Dalton Dietrich, Shu Wu
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87706-w