HDACs and the senescent phenotype of WI-38 cells

<p>Abstract</p> <p>Background</p> <p>Normal cells possess a limited proliferative life span after which they enter a state of irreversible growth arrest. This process, known as replicative senescence, is accompanied by changes in gene expression that give rise to a vari...

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Bibliographic Details
Main Authors: Noonan Emily J, Place Robert F, Giardina Charles
Format: Article
Language:English
Published: BMC 2005-10-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/6/37