Alpha-lipoic acid attenuates cardiac fibrosis in Otsuka Long-Evans Tokushima Fatty rats

Alpha-lipoic acid attenuates cardiac fibrosis in Otsuka Long-Evans Tokushima Fatty rats

<p>Abstract</p> <p>Background</p> <p>Hyperglycemia leads to cardiac oxidative stress and an imbalance in glucose homeostasis. Diabetic cardiomyopathy is characterised by cardiac hypertrophy and fibrosis. However, the underlying mechanisms of diabetic cardiomyopathy are...

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Bibliographic Details
Main Authors: Lee Jung Eun, Yi Chin-ok, Jeon Byeong Tak, Shin Hyun Joo, Kim Soo Kyoung, Jung Tae Sik, Choi Jun Young, Roh Gu Seob
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Cardiovascular Diabetology
Subjects:
Alpha-lipoic acid
Cardiac fibrosis
OLETF rat
Online Access:http://www.cardiab.com/content/11/1/111

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