Long-term potentiation in spinal nociceptive pathways as a novel target for pain therapy

<p>Abstract</p> <p>Long-term potentiation (LTP) in nociceptive spinal pathways shares several features with hyperalgesia and has been proposed to be a cellular mechanism of pain amplification in acute and chronic pain states. Spinal LTP is typically induced by noxious input and has...

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Bibliographic Details
Main Authors: Liu Xian-Guo, Drdla Ruth, Wilder-Smith Oliver, Ruscheweyh Ruth, Sandkühler Jürgen
Format: Article
Language:English
Published: SAGE Publishing 2011-03-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/7/1/20