In Vitro Models for Studying Entry, Tissue Tropism, and Therapeutic Approaches of Highly Pathogenic Coronaviruses

Coronaviruses (CoVs) are enveloped nonsegmented positive-sense RNA viruses belonging to the family Coronaviridae that contain the largest genome among RNA viruses. Their genome encodes 4 major structural proteins, and among them, the Spike (S) protein plays a crucial role in determining the viral tr...

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Bibliographic Details
Main Authors: Saeid Najafi Fard, Linda Petrone, Elisa Petruccioli, Tonino Alonzi, Giulia Matusali, Francesca Colavita, Concetta Castilletti, Maria Rosaria Capobianchi, Delia Goletti
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2021/8856018