LncRNA SENCR suppresses abdominal aortic aneurysm formation by inhibiting smooth muscle cells apoptosis and extracellular matrix degradation

LncRNA SENCR suppresses abdominal aortic aneurysm formation by inhibiting smooth muscle cells apoptosis and extracellular matrix degradation

Abdominal aortic aneurysm (AAA) is a progressive chronic dilatation of the abdominal aorta without effective medical treatment. This study aims to clarify the potential of long non-coding RNA SENCR as a treatment target in AAA. Angiotensin II (Ang-II) was used to establish AAA mouse model as well a...

Full description

Bibliographic Details
Main Authors: Zhou Cai, Jianhua Huang, Junxiao Yang, Baihong Pan, Wei Wang, Yangyang Ou, Xianwei Wang, Pu Yang
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2020-09-01
Series:Bosnian Journal of Basic Medical Sciences
Subjects:
Abdominal aortic aneurysm
lncRNA SENCR
vascular smooth muscle cells
cell apoptosis
extracellular matrix degradation
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/4994

Similar Items

Similar Items