Human tissue models in cancer research: looking beyond the mouse
Mouse models, including patient-derived xenograft mice, are widely used to address questions in cancer research. However, there are documented flaws in these models that can result in the misrepresentation of human tumour biology and limit the suitability of the model for translational research. A c...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
The Company of Biologists
2017-08-01
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| Series: | Disease Models & Mechanisms |
| Online Access: | http://dmm.biologists.org/content/10/8/939 |