Effects of 3-year denosumab treatment on hip structure in Japanese postmenopausal women and men with osteoporosis

Denosumab, a human monoclonal antibody against RANK ligand, is shown to have strong anti-fracture effects in Japanese osteoporosis patients. However, there have been no data showing actions on Japanese bone architecture. Here we show that denosumab continuously improves several geometrical parameter...

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Bibliographic Details
Main Authors: Teruki Sone, Naohiro Kon, Kenneth W. Gaither, Naoki Okubo, Taisuke Osakabe, Yutaka Nakayama, Masao Fukunaga, Masako Ito, Toshitaka Nakamura
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Bone Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187217300360